Description
SLU-PP-332 research compound
SLU-PP-332 is a synthetic small molecule that acts as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ, with the highest potency at ERRα. These nuclear receptors help regulate genes involved in mitochondrial biogenesis and oxidative metabolism. In the laboratory, SLU-PP-332 is used as a tool compound in cell-based research on mitochondrial respiration and energy metabolism.
Unlike most products in our range, SLU-PP-332 is not a peptide. Supplied as a powder in a 5mg vial. It is not a licensed medicine in the UK. We supply it strictly as a research reagent.
Specifications
| Name | SLU-PP-332 |
|---|---|
| Class | Small-molecule pan-ERR agonist (ERRα, ERRβ, ERRγ) |
| Chemical name | 4-hydroxy-N′-(2-naphthalenylmethylene)benzohydrazide |
| Molecular formula | C18H14N2O2 |
| Molecular weight | ≈ 290.3 g/mol |
| CAS number | 303760-60-3 |
| Form | Solid powder in a sealed glass vial |
| Size | 5mg |
Where SLU-PP-332 fits in research
Quality and testing
Read more about our process on the Quality & Testing page.
Storage and handling
Store the powder at −20 °C, sealed and protected from light and moisture. Allow the vial to reach room temperature before opening to limit condensation. SLU-PP-332 has low water solubility, so it is usually dissolved in an organic solvent such as DMSO. Prepare solutions according to your laboratory’s validated protocols, using appropriate PPE.
Frequently asked questions
What is SLU-PP-332?
SLU-PP-332 is a synthetic small molecule that acts as an agonist of the estrogen-related receptors ERRα, ERRβ and ERRγ, with the highest potency at ERRα. It is studied in vitro in research on mitochondrial function and the regulation of cellular energy metabolism.
Is SLU-PP-332 a peptide?
No. SLU-PP-332 is a small molecule (a benzohydrazide derivative), not a peptide. It is listed alongside our research peptides because it is used in related areas of metabolic and mitochondrial research.
What are estrogen-related receptors?
Estrogen-related receptors (ERRα, ERRβ and ERRγ) are nuclear receptors involved in regulating genes linked to mitochondrial biogenesis and oxidative metabolism. Despite the name, they do not bind oestrogen. SLU-PP-332 is used as a tool compound to activate them in laboratory models.
What is the chemical structure of SLU-PP-332?
Its chemical name is 4-hydroxy-N′-(2-naphthalenylmethylene)benzohydrazide. The molecular formula is C18H14N2O2, with a molecular weight of about 290.3 g/mol and CAS number 303760-60-3.
How is SLU-PP-332 dissolved in the lab?
As a small molecule with low water solubility, SLU-PP-332 is usually dissolved in an organic solvent such as DMSO for in vitro work. Solubility and solvent compatibility should be confirmed within your own laboratory protocol.
What purity is your SLU-PP-332?
Every batch is purity tested by Janoshik, an independent laboratory, using HPLC before it is released for sale.
How should SLU-PP-332 be stored?
Store the powder sealed at −20 °C, protected from light and moisture. Allow the vial to reach room temperature before opening. Stability in solution should be validated within your own laboratory protocol.
Do you ship SLU-PP-332 from the UK?
Yes. Orders placed before 3PM UK time, Monday to Friday, are normally dispatched the same day by Royal Mail Tracked 24. See our Shipping Policy.
Do you provide dosing or usage advice?
No. SLU-PP-332 is supplied for in vitro laboratory research only. We do not provide dosage, administration or medical advice of any kind.
Research use only. This product is supplied strictly for in vitro laboratory research. It is not for human or animal use, and not for diagnostic or therapeutic purposes. By purchasing, you agree to our Research Use Disclaimer.
